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Nicholas C Turner Selected Research

palbociclib

1/2022Overall Survival with Palbociclib and Fulvestrant in Women with HR+/HER2- ABC: Updated Exploratory Analyses of PALOMA-3, a Double-blind, Phase III Randomized Study.
1/2021Evaluation of the Association of Polymorphisms With Palbociclib-Induced Neutropenia: Pharmacogenetic Analysis of PALOMA-2/-3.
1/2021Long-Term Pooled Safety Analysis of Palbociclib in Combination with Endocrine Therapy for Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: Updated Analysis with up to 5 Years of Follow-Up.
1/2021Circulating Tumor DNA Markers for Early Progression on Fulvestrant With or Without Palbociclib in ER+ Advanced Breast Cancer.
1/2021Triplet Therapy with Palbociclib, Taselisib, and Fulvestrant in PIK3CA-Mutant Breast Cancer and Doublet Palbociclib and Taselisib in Pathway-Mutant Solid Cancers.
1/2021Prognostic Factors for Overall Survival in Patients with Hormone Receptor-Positive Advanced Breast Cancer: Analyses From PALOMA-3.
11/2020Treatment effect of palbociclib plus endocrine therapy by prognostic and intrinsic subtype and biomarker analysis in patients with bone-only disease: a joint analysis of PALOMA-2 and PALOMA-3 clinical trials.
10/2019Cyclin E1 Expression and Palbociclib Efficacy in Previously Treated Hormone Receptor-Positive Metastatic Breast Cancer.
2/2019Palbociclib and Fulvestrant in Breast Cancer. Reply.
1/2019Long-term Pooled Safety Analysis of Palbociclib in Combination With Endocrine Therapy for HR+/HER2- Advanced Breast Cancer.
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Nicholas C Turner Research Topics

Disease

57Breast Neoplasms (Breast Cancer)
10/2022 - 08/2006
48Neoplasms (Cancer)
01/2022 - 02/2008
8Neutropenia
01/2021 - 07/2015
5Disease Progression
01/2022 - 07/2015
4Infections
01/2021 - 01/2017
4Triple Negative Breast Neoplasms
01/2021 - 12/2010
3Febrile Neutropenia
01/2021 - 07/2015
3Fatigue
10/2020 - 07/2015
2Exanthema (Rash)
10/2020 - 10/2020
2Ovarian Neoplasms (Ovarian Cancer)
11/2017 - 01/2016
2Leukopenia
01/2017 - 07/2015
2Lung Neoplasms (Lung Cancer)
01/2015 - 12/2010
1Lobular Carcinoma
04/2022
1Microsatellite Instability
01/2022
1Circulating Neoplastic Cells
01/2022
1Interstitial Lung Diseases (Interstitial Lung Disease)
01/2021
1Diarrhea
10/2020
1Hypertension (High Blood Pressure)
01/2020
1Squamous Cell Carcinoma (Epidermoid Carcinoma)
01/2020
1Genetic Translocation (Chromosomal Translocation)
01/2017
1Cholangiocarcinoma
01/2017
1Bone Diseases (Bone Disease)
04/2016
1Neoplasm Metastasis (Metastasis)
04/2016
1Melanoma (Melanoma, Malignant)
01/2016
1Stomach Neoplasms (Stomach Cancer)
01/2016
1Colorectal Neoplasms (Colorectal Cancer)
01/2016
1Oncogene Addiction
01/2016
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2016
1Glioblastoma (Glioblastoma Multiforme)
01/2016
1Residual Neoplasm
08/2015
1Thrombocytopenia (Thrombopenia)
07/2015
1Anemia
07/2015

Drug/Important Bio-Agent (IBA)

22palbociclibIBA
01/2022 - 07/2015
19Fulvestrant (Faslodex)FDA Link
01/2022 - 07/2015
19Hormones (Hormone)IBA
01/2022 - 07/2015
14Circulating Tumor DNAIBA
01/2022 - 08/2015
12Estrogen ReceptorsIBA
01/2021 - 08/2011
8ErbB Receptors (EGF Receptor)IBA
01/2022 - 07/2015
8Phosphotransferases (Kinase)IBA
01/2017 - 08/2011
7Poly(ADP-ribose) Polymerase InhibitorsIBA
10/2020 - 05/2008
6Biomarkers (Surrogate Marker)IBA
01/2022 - 01/2016
6DNA (Deoxyribonucleic Acid)IBA
01/2021 - 01/2013
6Cyclin-Dependent Kinase 4IBA
01/2021 - 01/2017
5Cyclin-Dependent Kinases (cdk Proteins)IBA
01/2020 - 02/2015
4capivasertibIBA
10/2020 - 01/2020
4PlatinumIBA
01/2019 - 11/2012
3Cell-Free Nucleic AcidsIBA
01/2022 - 11/2017
3Phenobarbital (Luminal)FDA Link
11/2020 - 12/2013
3human ERBB2 proteinIBA
01/2020 - 10/2016
3Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
06/2012 - 12/2010
2eribulinFDA Link
10/2022 - 10/2021
2Vinorelbine (Navelbine)FDA LinkGeneric
10/2022 - 10/2021
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
01/2022 - 10/2020
2Aromatase InhibitorsIBA
10/2020 - 01/2016
2exemestane (Aromasin)FDA Link
10/2020 - 01/2016
2olaparibIBA
10/2020 - 01/2017
2Paclitaxel (Taxol)FDA LinkGeneric
10/2020 - 01/2020
2CyclinsIBA
10/2019 - 01/2016
2LigandsIBA
06/2012 - 08/2011
2Proteins (Proteins, Gene)FDA Link
12/2008 - 08/2006
1TubulinIBA
10/2022
1Tubulin ModulatorsIBA
10/2022
1Cadherins (E-Cadherin)IBA
04/2022
1Cell Adhesion MoleculesIBA
04/2022
1pembrolizumabIBA
01/2022
1N 30IBA
01/2022
1AlpelisibIBA
01/2022
1Immune Checkpoint InhibitorsIBA
01/2022
1dostarlimabIBA
01/2022
1niraparibIBA
10/2021
1Capecitabine (Xeloda)FDA Link
10/2021
1GemcitabineFDA Link
10/2021
1tetrachloroisophthalonitrile (Bravo)IBA
10/2021
1Ado-Trastuzumab EmtansineIBA
10/2021
12- (3- (2- (1- isopropyl- 3- methyl- 1H- 1,2- 4- triazol- 5- yl)- 5,6- dihydrobenzo(f)imidazo(1,2- d)(1,4)oxazepin- 9- yl)- 1H- pyrazol- 1- yl)- 2- methylpropanamideIBA
01/2021
1gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA
10/2020
1neratinibIBA
10/2020
1InterferonsIBA
01/2020
1E-3810IBA
01/2020
1rucaparibIBA
01/2020
1talazoparibIBA
01/2019
1Tyrosine Kinase InhibitorsIBA
01/2019
1SaltsIBA
01/2017
1adavosertibIBA
01/2017
1Therapeutic UsesIBA
01/2017
1Goserelin (Zoladex)FDA Link
01/2017
1Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2017
1Pharmaceutical PreparationsIBA
10/2016
1Cytostatic AgentsIBA
01/2016
1AZD4547IBA
01/2016
1Anastrozole (Arimidex)FDA LinkGeneric
01/2016
1abemaciclibIBA
01/2016
1DNA HelicasesIBA
04/2015

Therapy/Procedure

41Therapeutics
01/2022 - 02/2008
14Drug Therapy (Chemotherapy)
10/2022 - 12/2010
3Adjuvant Chemotherapy
10/2021 - 10/2019
3Neoadjuvant Therapy
10/2019 - 12/2010
2Radiotherapy
01/2022 - 01/2020
1Drug Tapering
10/2016
1Intramuscular Injections
04/2016